Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy

Completed

Conditions studied: Cervical Spondylotic Myelopathy

In brief

The primary purpose of this study is to compare anterior and posterior surgical approach in treatment of CSM in terms of surgical complications and neurological, functional, disease-specific and quality of life outcomes measures. Secondary aims are to quantify the amount of change pre and post-surgery concerning the same outcome measures; to determine if there are differences in outcomes between posterior surgical techniques (i.e. laminectomy with fusion or laminoplasty) and examine the relationship between baseline MRI and baseline and follow-up neurological and functional outcomes.

Key facts

Study ID

NCT00285337

Run by

AOSpine North America Research Network

People needed

321

Starts

2005-12-01

Expected to finish

2007-11-01

Last updated by the study team

2017-11-01

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients undergo surgery for symptomatic cervical spondylotic myelopathy with one or or more of the following symptoms: Numb clumsy hands, impairment of gait, bilateral arm parasthesia, L'Hermitte's phenomena
• and one or more of the following signs: corticospinal distribution motor deficits, athropy of hand intrinsic muscles, hyperflexia, positive Hoffman sign, upgoing plantar responses, lower limb spasticity, broad based unstable gait

You may not qualify if…

• Asymptomatic cervical spondylotic myelopathy
• previous surgery for CSM
• Active infection
• Neoplastic disease
• Rheumatoid arthritis
• Ankylosing spondylitis
• Trauma
• Concomitant lumbar stenosis
• Not referred for surgical consultation
• Participating in other trials or unlikely to attend follow-ups

Where it is running

• Spine Education and Research Institute — Thornton, Colorado, United States
• Emory University — Atlanta, Georgia, United States
• Indianda Spine Group — Indianapolis, Indiana, United States
• Kansas University Medical Center — Kansas City, Kansas, United States
• John Hopkins University — Baltimore, Maryland, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• New England Baptist Hospital — Boston, Massachusetts, United States
• Mayo Clinic — Rochester, Minnesota, United States
• Thomas Jefferson University and Rothman Institure Orthopaedics — Philadelphia, Pennsylvania, United States
• Universty of Utah — Salt Lake City, Utah, United States
• University Of Virginia — Charlottesville, Virginia, United States
• Harborview Medical Center — Seattle, Washington, United States
• University of Toronto — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

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