Comparing Angiography: Multislice CT Versus Invasive Heart Catheterization (CACTI)

Completed · Not applicable

Conditions studied: Coronary Arteriosclerosis

In brief

The purpose of the study is to compare the pictures of heart arteries obtained by MSCT scanner to the pictures obtained during heart catheterization. Our specific question is whether the MSCT scanner is accurate enough to replace heart catheterization in some situations for the evaluation of coronary heart disease.

Key facts

Study ID

NCT00284466

Run by

University of Wisconsin, Madison

People needed

50

Starts

2006-01-01

Expected to finish

2006-08-01

Last updated by the study team

2012-08-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects >18 years old with stable clinical symptoms who are scheduled for outpatient cardiac catheterization.
• Able to provide written informed consent in accordance with the IRB.

You may not qualify if…

• Symptoms of unstable angina/acute coronary syndrome
• Known allergy or adverse reaction to CT radiocontrast and/or iodine.
• Known absolute contraindication to Metoprolol.
• Significant kidney disease including creatinine > 1.5 mg/dL or GFR < 60 ml/min.
• Inability to breath-hold for up to 30 seconds.
• Women who are Pregnant or Nursing
• Atrial Fibrillation or any other arrhythmia that makes attaining a regular slow rhythm unlikely.
• History of previous stent placement or coronary bypass surgery.

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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