Ph II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC
Completed · Phase 2
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether gemcitabine and erlotinib are more effective when given alone or together in treating non-small cell lung cancer. PURPOSE: This randomized phase II trial is studying gemcitabine and erlotinib to compare how well they work when given alone or together as first-line therapy in treating older patients with stage IIIB or stage IV non-small cell lung cancer.
Key facts
- Study ID
- NCT00283244
- Run by
- UNC Lineberger Comprehensive Cancer Center
- People needed
- 147
- Starts
- 2006-03-01
- Expected to finish
- 2014-10-01
- Last updated by the study team
- 2017-04-24
Who can join
Age: 70 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Highlands Oncology Group - Fayetteville — Fayetteville, Arkansas, United States
- Summit Cancer Care — Savannah, Georgia, United States
- Evanston Hospital — Evanston, Illinois, United States
- Hackensack University Medical Center Cancer Center — Hackensack, New Jersey, United States
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
- Blumenthal Cancer Center at Carolinas Medical Center — Charlotte, North Carolina, United States
- Batte Cancer Center at Northeast Medical Center — Concord, North Carolina, United States
- Cape Fear Valley Medical Center Cancer Center — Fayetteville, North Carolina, United States
- Rex Cancer Center at Rex Hospital — Raleigh, North Carolina, United States
- Kingsport Hematology-Oncology Associates — Kingsport, Tennessee, United States
- University of Tennessee Cancer Institute - Memphis — Memphis, Tennessee, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.