Outcomes With Tight Control of Hyperglycemia in Cardiac Surgery Patients

Completed · Phase 3

Conditions studied: Cardiac Surgical Procedures, Hyperglycemia

In brief

Patients with or without diabetes may have high blood sugar levels due to stress response of the body during heart surgery. This study is being done to determine if maintaining normal blood sugar levels during open-heart surgery by using intravenous insulin results in a lesser incidence of death, wound infections in the chest, disturbances of heart rhythm, kidney failure, stroke and prolonged time on the breathing machine (artificial ventilation) within 30 days after surgery.

Key facts

Study ID

NCT00282698

Run by

Mayo Clinic

People needed

400

Starts

2004-07-01

Expected to finish

2005-05-01

Last updated by the study team

2011-05-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All subjects accepted for this study must be:
• >=18 years of age
• Undergoing an elective cardiac surgical procedure

You may not qualify if…

• Subjects who have one or more of the following will be excluded from the study:
• Undergoing surgery not utilizing cardiopulmonary bypass
• Unable to grant informed consent or comply with study procedure
• Undergoing emergency open heart-surgery
• Are allergic to any of the excipients in insulin

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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