Partial Breast Irradiation With Chemotherapy

Completed · Phase 1/Phase 2

Conditions studied: Breast Cancer

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cyclophosphamide and doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with cyclophosphamide and doxorubicin after surgery may kill any tumor cells that remain. PURPOSE: This phase I/II trial is studying the side effects of radiation therapy when given together with cyclophosphamide and doxorubicin and to see how well they work in treating women with stage I or stage II breast cancer who have undergone surgery.

Key facts

Study ID
NCT00278109
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
People needed
27
Starts
2004-07-01
Expected to finish
2016-12-01
Last updated by the study team
2020-02-19

Who can join

Age: 40 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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