Sertraline for the Prevention of Recurrent Postpartum Depression

Completed · Phase 3

Conditions studied: Depression

In brief

This study will determine the effectiveness of taking sertraline within 24 hours of giving birth in preventing a recurrence of postpartum depression.

Key facts

Study ID

NCT00276900

Run by

University of Pittsburgh

People needed

300

Starts

2003-12-01

Expected to finish

2006-08-01

Last updated by the study team

2013-10-07

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Pregnant
• Presents by week 36 gestation for first two study visit interviews (interviews may be combined)
• History of DSM-IV Major Depression after the age of 15
• Score no higher than 19 on the 29-item SIGH-ADS at Week 36
• Medically healthy, as determined by a physician

You may not qualify if…

• Current major depression
• Urine screen positive for drugs
• Currently using other therapies for depression
• DSM-IV diagnoses of bipolar 1 or 2 disorder or any psychotic episode
• History of substance abuse within 6 months prior to study entry
• Has not received any obstetrical care
• Use of medications for medical disorders (except for treatment of stable disorders)

Where it is running

• Women's Behavioral HealthCare Program — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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