Mechanisms of Resistance and Molecular Epidemiology of Commonly Encountered Multi-Resistant Bacteria

Completed

Conditions studied: Bacterial Infection

In brief

o determine if extended-spectrum beta-lactamases, plasmid-mediated AmpC beta-lactamases, carbapenemases, chromosomal mutations in ribosomal RNA or other mechanisms of resistance account for antibiotic resistance in commonly encountered Gram negative and Gram positive bacteria at UPMC. Also to determine the molecular epidemiology and in vitro susceptibility of multiply resistant organisms at UPMC and to relate this to antibiotic use in the institution.

Key facts

Study ID

NCT00275327

Run by

University of Pittsburgh

People needed

300

Starts

2006-01-01

Expected to finish

2015-12-01

Last updated by the study team

2015-12-17

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• bacteria resistant to commonly used antibiotics

Where it is running

• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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