PET Imaging and Olanzapine Treatment in Borderline Personality Disorder

Completed · Not applicable

Conditions studied: Borderline Personality Disorder

In brief

The overall design of the study is to perform both a PET and MRI scan on objectively identified borderline personality disorder patients, to treat them with olanzapine for 8 weeks, and to then re-scan the patients with PET.

Key facts

Study ID

NCT00275301

Run by

University of Minnesota

People needed

19

Starts

2005-12-01

Expected to finish

2008-12-01

Last updated by the study team

2017-05-23

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age 18-45 years
• Diagnosis: borderline personality disorder by DSM-IV criteria
• Gender: Female
• May have history of substance use and other Axis II disorders

You may not qualify if…

• Axis I diagnosis of schizophrenia, schizoaffective disorder, or bipolar I disorder during the subject's lifetime. No current major depression or PTSD.
• Treatment with psychotropic medication in the previous month.
• Medical disorder that would influence outcome of the study - e.g. epilepsy, thyroid disease, HIV, etc.
• Medical disorder that would not allow use of olanzapine
• Active substance abuse or dependence
• Previous adverse reaction to olanzapine
• Females whom are pregnant or nursing

Where it is running

• University of Minnesota, Dept of Psychiatry — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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