Chromoendoscopy for Ulcerative Colitis Surveillance

Completed

Conditions studied: Ulcerative Colitis, Crohn's Disease

In brief

Long-standing ulcerative colitis is associated with an increased cancer risk. Chromoendoscopy with dye spraying can detect subtle abnormalities that are not visible with standard endoscopy. The purpose of this study is to determine if chromoendoscopy with fewer "targeted biopsies" can replace standard colonoscopy with multiple "random" biopsies.

Key facts

Study ID

NCT00274209

Run by

Indiana University

People needed

100

Starts

2005-12-01

Expected to finish

2011-11-01

Last updated by the study team

2011-11-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ulcerative colitis, pancolitis > 8 years; left-sided > 15 years or
• history of PSC or
• history of previous dysplasia on colon biopsies or
• family history of colon cancer in first degree relative

You may not qualify if…

• any condition that precludes colonoscopy
• expected survival less than 1 year

Where it is running

• Indiana University Medical Center — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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