Lumigan Versus Cosopt

Completed · Phase 4 · Has a placebo group

Conditions studied: Open-Angle Glaucoma

In brief

To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy

Key facts

Study ID

NCT00273455

Run by

Pharmaceutical Research Network

People needed

34

Starts

2006-01-01

Expected to finish

2007-05-01

Last updated by the study team

2008-11-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adults with a diagnosis of bilateral open-angle glaucoma including: primary, pigment dispersion or exfoliation in both eyes
• on no therapy the intraocular pressure should be 22-29 mm Hg inclusive at the 8:00 AM measurement
• visual acuity should be 20/200 or better in each eye

You may not qualify if…

• historical failure to respond to topical beta-blockers in a clinically meaningful manner
• any contraindication to study medications
• any anticipated change, or modification in the 6 weeks prior to Visit 1, in systemic hypertensive therapy during the trial

Where it is running

• Taustine Eye Center — Louisville, Kentucky, United States
• Glaucoma Consultants & Center for Eye Research, PA — Mt. Pleasant, South Carolina, United States
• Houston Eye Associates — Houston, Texas, United States

Full record on ClinicalTrials.gov

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