Cosopt Versus Xalatan

Completed · Phase 4 · Has a placebo group

Conditions studied: Open-Angle Glaucoma, Ocular Hypertension

In brief

To compare the 24-hour efficacy and safety, measured every three hours, of the dorzolamide/timolol fixed combination given twice daily versus latanoprost and placebo each given once daily.

Key facts

Study ID

NCT00273429

Run by

Pharmaceutical Research Network

Starts

2005-04-01

Expected to finish

2005-12-01

Last updated by the study team

2007-01-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adults with primary open-angle, pigmentary, or exfoliation glaucoma, or ocular hypertenstion
• intraocular pressure should be 22 to 30 mm Hg inclusive on timolol BID at the 08:00 H
• ETDRS visual acuity must be 1.0 or better in both eyes

You may not qualify if…

• any contraindications to study medications
• any anticipated change in systemic hypertensive therapy during the trial

Where it is running

• Central Florida Eye Associates — Lakeland, Florida, United States
• Midwest Eye Center SC — Bourbonnais, Illinois, United States

Full record on ClinicalTrials.gov

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