Clinical and Genetic Studies in Families With Myopia and Related Diseases

Completed

Conditions studied: Myopia

In brief

This study will examine the inheritance of myopia in families of various nationalities and ethnic backgrounds to identify gene changes that cause myopia or similar diseases and to better understand these conditions. In patients with myopia, the eye does not focus light accurately on the retina (tissue that lines the back of the eye), so that objects at a distance appear blurry. Myopia may occur alone, with other vision problems such as retinal dislocations, cataract or glaucoma, or with other problems such as joint or skin problems. People with myopia (usually those from families with several affected members) and control subjects with normal vision may be eligible for this study. Each participant undergoes the following procedures: * Blood draw for genetic testing related to the disorders under study * Medical and family history, including drawing a family tree to explore vision problems in the family * Complete eye examination, including refraction (pupil dilation) and visual acuity testing, photographs of the retina and possibly lens, and specialized tests to measure field of vision, color vision and ability to see in the dark

Key facts

Study ID
NCT00272376
Run by
National Eye Institute (NEI)
People needed
851
Starts
2005-12-21
Expected to finish
2016-07-29
Last updated by the study team
2019-12-12

Who can join

Age: 4 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

Where it is running

Full record on ClinicalTrials.gov

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