Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents

Completed

Conditions studied: Sleep Deprivation

In brief

Work requirements for medical trainees result in substantial sleep loss. Sleep loss has been associated with increased levels of certain inflammatory hormones that could have negative impact on blood vessel function. The purpose of this study is to determine the effects of sleep loss on blood hormone levels and blood vessel function in medical trainees.

Key facts

Study ID

NCT00272233

Run by

Yale University

People needed

22

Starts

2004-12-01

Expected to finish

2005-06-01

Last updated by the study team

2007-03-20

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Medical resident in MICU rotation
• Non-smoker
• Body mass index <28 kg/m2

You may not qualify if…

• Systolic blood pressure >140 mmHg; Diastolic blood pressure >90 mmHg
• Known history of diabetes mellitus, hypertension, hyperlipidemia
• Known history of acute or chronic inflammatory or infectious disease
• Known history of sleep disturbance unrelated to work
• Pregnancy

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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