Exercise to Reduce Obesity in Spinal Cord Injury

Completed · Not applicable

Conditions studied: Diabetes Mellitus, Obesity, Paraplegia, Quadriplegia, Spinal Cord Injury

In brief

The purpose of this proposal was to evaluate and compare the health benefits of using upper extremity exercise versus functional electrical stimulation for lower extremity exercise. It was our hypothesis that both Functional Electrical Stimulation Leg Cycle Ergometry (FES LCE) exercise and voluntary Arm Crank Ergometry (ACE) upper extremity exercise would increase whole body energy expenditure, thereby increasing muscle mass, insulin sensitivity, glucose effectiveness and improving lipid profiles in adults with paraplegia.

Key facts

Study ID

NCT00270855

Run by

VA Office of Research and Development

People needed

29

Starts

2008-05-01

Expected to finish

2011-12-01

Last updated by the study team

2017-11-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Criteria for participation included men and women within the age range of 18-65 years old with BMI>25 kg/m2 who have had T4-L2 Motor-Complete (ASIA A\&B) SCI for duration of greater than 12 months to ensure a homogenous sample.

You may not qualify if…

• persons who were unresponsive to surface neurostimulation
• had participated in an FES or ACE exercise (> 60 minutes/week) program within the past 3 months
• and those with known orthopedic limitations
• CAD
• diabetes mellitus (fasting glucose>126 or HgbA1c>7.0) or known family history
• hypothyroidism
• and/or renal disease were excluded from the study.
• Additionally, individuals with uncontrolled autonomic dysreflexia, recent (within 3 months) deep vein thrombosis, or pressure ulcers > Grade II were excluded.

Where it is running

• Hunter Holmes McGuire VA Medical Center — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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