Pemetrexed Disodium and Bevacizumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Completed · Phase 2
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving pemetrexed disodium together with bevacizumab may be an effective treatment for non-small cell lung cancer. PURPOSE: This phase II trial is studying how well giving pemetrexed disodium together with bevacizumab works in treating patients with stage III or stage IV non-small cell lung cancer.
Key facts
- Study ID
- NCT00268489
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 48
- Starts
- 2006-05-01
- Expected to finish
- 2010-04-01
- Last updated by the study team
- 2016-07-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Eden Medical Center — Castro Valley, California, United States
- Saint Rose Hospital — Hayward, California, United States
- Highland General Hospital at St. George's University School of Medicine — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Valley Care Medical Center — Pleasanton, California, United States
- Doctors Medical Center - San Pablo Campus — San Pablo, California, United States
- Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
- Piedmont Hospital — Atlanta, Georgia, United States
- Northside Hospital Cancer Center — Atlanta, Georgia, United States
- Saint Joseph's Hospital of Atlanta — Atlanta, Georgia, United States
- CCOP - Atlanta Regional — Atlanta, Georgia, United States
- WellStar Cobb Hospital — Austell, Georgia, United States
- Charles B. Eberhart Cancer Center at DeKalb Medical Center — Decatur, Georgia, United States
- Gwinnett Medical Center — Lawrenceville, Georgia, United States
- Kennestone Cancer Center at Wellstar Kennestone Hospital — Marietta, Georgia, United States
- Southern Regional Medical Center — Riverdale, Georgia, United States
- Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah, Georgia, United States
- Pearlman Comprehensive Cancer Center at South Georgia Medical Center — Valdosta, Georgia, United States
- Saint Anthony's Hospital at Saint Anthony's Health Center — Alton, Illinois, United States
- Rush-Copley Cancer Care Center — Aurora, Illinois, United States
- St. Joseph Medical Center — Bloomington, Illinois, United States
- Providence Cancer Center — Anchorage, Alaska, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.