Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)
Completed · Not applicable
Conditions studied: Coronary Arteriosclerosis
In brief
In this multicenter, international study we are evaluating two approaches to determine which coronary artery narrowings require stent placement in patients with multivessel coronary artery disease. Patients will be randomized to an angiographic strategy, where only coronary angiography is used to determine which lesions to stent or to a pressure wire strategy where fractional flow reserve, an index measured with the pressure wire, will be used to determine which lesions to stent. The primary outcome will be major adverse cardiac events at 1 year. A secondary outcome will be cost-effectiveness.
Key facts
- Study ID
- NCT00267774
- Run by
- Stanford University
- People needed
- 1005
- Starts
- 2006-01-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2017-11-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Stanford University School of Medicine — Stanford, California, United States
- Catharina Hospital — Eindhoven, Netherlands
Full record on ClinicalTrials.gov
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