A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).

Stopped early · Phase 3

Conditions studied: Hyperlipidemia, Dyslipidemia, Hypercholesterolemia

In brief

The Torcetrapib project was terminated on December 2, 2006 due to safety findings. Cholesterol levels will be measured over six weeks in subjects being treated with two different kinds of cholesterol medications to see how the different treatments compare to one another.

Key facts

Study ID

NCT00267280

Run by

Pfizer

People needed

640

Starts

2006-01-01

Expected to finish

2006-12-01

Last updated by the study team

2012-02-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• eligible for statin treatment for LDL cholesterol by NCEP guidelines

You may not qualify if…

• Women who are pregnant or lactating, or planning to become pregnant.
• Subjects taking any drugs known to be associated with an increased risk of myositis in combination with HMG-CoA reductase inhibitors.
• Subjects with significant liver or kidney disease or significant heart failure.

Where it is running

• Pfizer Investigational Site — Mesa, Arizona, United States
• Pfizer Investigational Site — Alhambra, California, United States
• Pfizer Investigational Site — Inglewood, California, United States
• Pfizer Investigational Site — Los Angeles, California, United States
• Pfizer Investigational Site — Santa Ana, California, United States
• Pfizer Investigational Site — Wilmington, Delaware, United States
• Pfizer Investigational Site — Fort Lauderdale, Florida, United States
• Pfizer Investigational Site — Hollywood, Florida, United States
• Pfizer Investigational Site — Jacksonville, Florida, United States
• Pfizer Investigational Site — Merritt Island, Florida, United States
• Pfizer Investigational Site — Pensacola, Florida, United States
• Pfizer Investigational Site — Vero Beach, Florida, United States
• Pfizer Investigational Site — Winter Park, Florida, United States
• Pfizer Investigational Site — Atlanta, Georgia, United States
• Pfizer Investigational Site — Conyers, Georgia, United States
• Pfizer Investigational Site — Woodstock, Georgia, United States
• Pfizer Investigational Site — Hinsdale, Illinois, United States
• Pfizer Investigational Site — La Grange, Illinois, United States
• Pfizer Investigational Site — Park Ridge, Illinois, United States
• Pfizer Investigational Site — Springfield, Illinois, United States
• Pfizer Investigational Site — Kansas City, Kansas, United States
• Pfizer Investigational Site — Lexington, Kentucky, United States
• Pfizer Investigational Site — Baltimore, Maryland, United States
• Pfizer Investigational Site — Bethesda, Maryland, United States
• Pfizer Investigational Site — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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