Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome
Completed · Phase 4
Conditions studied: Turner Syndrome
In brief
This is an extension study that will gather long-term data on the effect of early growth hormone (GH) treatment on adult height and other aspects of health and development in girls with Turner syndrome. The main purpose is to determine whether girls who received 2 years of GH treatment before 6 years of age achieve taller adult height than girls who were untreated during this time. The study will also look at middle ear and hearing function, and cognitive and behavioral development. Protocol completion is defined as attainment of height velocity less than or equal to 1.0 cm/year, or bone age greater than or equal to 15 years.
Key facts
- Study ID
- NCT00266656
- Run by
- Eli Lilly and Company
- People needed
- 69
- Starts
- 2005-12-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2017-03-31
Who can join
Age: 4 and older, up to 20. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Previously randomized in study B9R-US-GDFG (NCT00406926)
- Karyotype-proven Turner syndrome
You may not qualify if…
- Immediate family members of study site personnel directly affiliated with the study
Where it is running
- Childrens Hospital of Los Angeles — Los Angeles, California, United States
- Children's Hospital — Aurora, Colorado, United States
- Connecticut Children's Medical Center — Hartford, Connecticut, United States
- Children's Hospital of Chicago Research Center — Chicago, Illinois, United States
- Riley Hosptial for Children — Indianapolis, Indiana, United States
- Children's Mercy Hospital — Kansas City, Missouri, United States
- University of NC at Chapel Hill School of Medicine — Chapel Hill, North Carolina, United States
- Thomas Jefferson University — Philadelphia, Pennsylvania, United States
- Childrens Hospital and Medical Center — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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