Cognitive Remediation for Schizophrenia

Completed · Not applicable

Conditions studied: Schizophrenia

In brief

The purpose of this study is to evaluate the efficacy of an innovative, computer driven cognitive rehabilitation program for unemployed veterans with schizophrenia.

Key facts

Study ID

NCT00261794

Run by

US Department of Veterans Affairs

People needed

90

Starts

2004-11-01

Expected to finish

2007-09-01

Last updated by the study team

2010-01-06

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current DSM-IV diagnoses of schizophrenia or schizoaffective disorder
• Stable clinical course and antipsychotic treatment on a new generation antipsychotic other than clozapine and/or a dose of first generation antipsychotic equivalent to 10 mg. or less of haloperidol for one month prior to enrollment
• Age between 18 and 64 years
• Voluntary consent after receiving full information about the study

You may not qualify if…

• Documented history of neurological disorder or significant head trauma with extended loss of consciousness
• Physical limitations (e.g., with hearing or vision) that would interfere substantially with the use of computer-based exercises
• Current treatment with a first generation antipsychotic medication at a dose equivalent to more than 10 mg. of haloperidol
• Current treatment with benztropine mesylate at a daily does greater than 4 mg
• Current treatment with trihexyphenidyl at a daily dose greater than 15 mg
• Current treatment that combines benztropine mesylate with trihexyphenidyl
• Current treatment with diphenhydramine
• Current competitive employment or participation (current or within past 3 months) in a program designed to secure competitive employment (e.g., CWT)
• Mini Mental Status Examination (MMSE) score of less than 23
• Diagnosis of current Substance Dependence according to DSM-IV criteria

Where it is running

• VA Maryland Health Care System, Baltimore — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.