Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease
Running, not enrolling
Conditions studied: Gastroesophageal Reflux Disease
In brief
The aims of this study are to create a prospective data base to evaluate the long term outcomes of medical and surgical treatment of gastroesophageal reflux disease (GERD); to measure standard outcomes as well as patient derived outcomes such as general and disease specific quality of life (QOL) issues and patient satisfaction; to refine the parameters that may identify patients who will benefit from surgery for GERD; and to identify possible determinants of failure of both medical and surgical treatments of reflux.
Key facts
- Study ID
- NCT00260572
- Run by
- University of Pittsburgh
- People needed
- 2500
- Starts
- 1999-04-01
- Expected to finish
- 2050-12-01
- Last updated by the study team
- 2026-04-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with reflux symptoms present for at least 6 months, caused by documented reflux. Reflux symptoms include:
- heartburn
- acid regurgitation
- waterbrash
- non-cardiac chest pain
- dyspepsia
- Reflux diagnosis either by endoscopy, upper gastrointestinal (GI), or 24 hour pH.
- Patients scheduled for surgical management of GERD and/or hiatal hernia
- Patients currently or commencing treatment with at least proton pump inhibitors or pro-motility agents.
You may not qualify if…
- Patients unable to comprehend or complete the QOL instruments.
- Patients less than 18 years of age.
Where it is running
- UPMC Department of Cardiothoracic Surgery — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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