Effects of Gynecological Age on LH Sensitivity to Energy Availability

Completed · Not applicable

Conditions studied: Anovulation, Amenorrhea, Infertility, Starvation

In brief

The purpose of this experiment is to investigate whether the dependence of luteinizing hormone pulsatility on energy availability declines during adolescence.

Key facts

Study ID

NCT00260286

Run by

Ohio University

People needed

18

Starts

2001-08-01

Expected to finish

2004-05-01

Last updated by the study team

2005-12-05

Who can join

Age: 18 and older, up to 34. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 5-8 or 14-18 years of gynecological age
• menstrual cycles of 26 to 32 days for the previous 3 months
• luteal phase length >11 days
• 18-32% body fat

You may not qualify if…

• smoking
• oral contraceptives
• hematocrit <35%
• diet with <35 or >55 kcal/kgFFM/day of energy
• habitually performing more than 60 minutes/week of aerobic exercise
• histories or evidence of heart, liver, or kidney disease, diabetes, menstrual or thyroid disorders, pregnancy, lactation, and congenital or acquired orthopedic abnormalities

Where it is running

• Ohio University — Athens, Ohio, United States

Full record on ClinicalTrials.gov

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