Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)

Completed · Phase 4

Conditions studied: Rheumatoid Arthritis

In brief

The purpose of this study is to 1)to determine if it is better to treat all early RA patients with methotrexate in combination with hydroxychloroquine plus sulfasalazine or in combination with etanercept or reserve this treatment for patients who do not appropriately respond to methotrexate alone and 2) to determine which combination of methotrexate therapy is better

Key facts

Study ID

NCT00259610

Run by

University of Alabama at Birmingham

People needed

755

Starts

2004-05-01

Expected to finish

2009-06-01

Last updated by the study team

2014-07-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have a diagnosis of RA for less than or equal to 3 years
• Be 18 years of age or older at the time of diagnosis

You may not qualify if…

• Pregnant or lactating women
• History of chronic infection, such as hepatitis, pneumonia, or chronic skin infections
• Active TB or evidence of latent TB

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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