Cognitive Behavioral Therapy for the Treatment of Depression-Related Insomnia
Completed · Not applicable
Conditions studied: Depression
In brief
This study will determine the effectiveness of cognitive behavioral therapy (CBT) in treating insomnia symptoms that are secondary to depression. This study will also determine how long the benefits of CBT will last and how the recurrence of insomnia is associated with the onset of new depressive episodes.
Key facts
- Study ID
- NCT00255905
- Run by
- University of Rochester
- People needed
- 45
- Starts
- 2004-07-01
- Expected to finish
- 2007-07-01
- Last updated by the study team
- 2013-06-28
Who can join
Age: 25 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- History of recurrent depression with the age of onset between 20 and 40 years of age
- At least one depressive episode within 2 years prior to study entry
- At least three discrete depressive episodes within 10 years prior to study entry
- Successful treatment for or resolution of last episode of depression
- Participants whose depression is in remission are eligible for study enrollment. Criteria for remission includes more than 3 consecutive weeks during which the patient does not meet DSM-IV criteria for depression; a Hamilton Rating Depression Scale score less than 6 and a Beck Depression Inventory (BDI) less than 6; no feelings of depression for at least 6 months prior to study entry; and have not taken depression medication for at least 3 months prior to study entry. Once enrolled in the study, these participants must score less than 6 on the weekly BDIs for the first 3 weeks of the study.
- Have experienced mental stability between depressive episodes
- Willing to discontinue over-the-counter or naturopathic remedies for insomnia or depression during the study
- Able to write and speak English fluently
You may not qualify if…
- Current use of maintenance antidepressant therapy
- History of a failure to respond to citalopram treatment
- Unstable medical or psychiatric illness other than major depressive disorder
- History of seizures or head injury
- Current substance or alcohol abuse
- Symptoms suggestive of sleep disorders other than insomnia
- Pregnancy or plan to become pregnant within 2 years of study entry
Where it is running
- University of Rochester Sleep and Neurophysiology Research Lab — Rochester, New York, United States
Full record on ClinicalTrials.gov
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