Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure

Completed

Conditions studied: Psychogenic Movement Disorders, Non-epileptic Seizures

In brief

This study will explore how the mind and the brain work to cause movement symptoms or seizures in people who do not have a recognized neurological or medical disorder. The study includes a check for psychiatric disorders, symptoms and their severity; psychiatric and personality questionnaires; and neuropsychological testing. Normal, healthy volunteers, people who have movement symptoms not due to a brain or medical disorder and people who have seizures not due to epilepsy may be eligible for this study. All candidates must be 18 years of age or older. All participants have a medical history, physical examination and psychological evaluation, including completion of questionnaires. People with movement symptoms or seizures have a symptoms evaluation. Some participants also undergo neuropsychological testing, including questionnaires, pen-and-paper or computerized tests, and motor tasks.

Key facts

Study ID

NCT00255411

Run by

National Institute of Neurological Disorders and Stroke (NINDS)

People needed

190

Starts

2005-11-09

Expected to finish

2009-02-24

Last updated by the study team

2017-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Patients for dissociation study:
• Diagnosis of probable or possible PMD using Fahn and Williams criteria.
• Patients with neurological disorders with elaboration of their underlying disease process including comorbid epilepsy.
• Patients with a medical condition that prevents them from taking part in the study.
• Patients with current suicidal ideation.
• Patients with a psychotic disorder.
• Patients with active substance abuse within the last 6 months.
• Patients below the age of 18.
• Patients who are not capable of consent.
• Patients with an IQ less than 55.
• Patients currently involved in lawsuits.
• Patients for cognitive study:
• Diagnosis of probable or possible PMD using Fahn and Williams criteria
• Patients with neurological disorders with elaboration of their underlying disease process including comorbid epilepsy
• Patients with a medical condition that prevents them from taking part in the study.
• Patients with a history of a neurological disorder (e.g. dementia, cerebrovascular accident, neurodegenerative disorder, inflammatory disorders or infections of the central nervous system) that may result in cognitive deficits.
• Patients with a history of traumatic brain injury resulting in loss of consciousness or amnesia lasting for more than a few seconds.
• Patients with a psychotic disorder or bipolar disorder
• Patients with a current major depression
• Patients with current moderate to severe anxiety (Hamilton Anxiety Rating Scale greater than 25)
• Patients with current attention deficit hyperactivity disorder.
• Patients with active substance abuse within the last 6 months.
• Patient with current suicidal ideation.
• Patients below the age of 18.
• Patients who are not capable of consent.

Where it is running

• National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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