INNO-105 in Patients With Solid Tumors
Stopped early · Phase 1
Conditions studied: Tumors
In brief
The safety, tolerability and pharmacokinetics of INNO-105, an investigational anticancer drug, are being studied in patients with solid tumors.
Key facts
- Study ID
- NCT00255333
- Run by
- Innovive Pharmaceuticals
- People needed
- 24
- Starts
- 2005-11-01
- Expected to finish
- 2007-03-01
- Last updated by the study team
- 2007-05-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Have a histologically or cytologically confirmed diagnosis of a solid malignancy (patients may have either measurable or nonmeasurable disease).
- Be ≥18 years old.
- Not eligible for effective therapy likely to provide clinical benefit.
- Have an Eastern Cooperative Oncology Group (ECOG) Performance Status of ≤2.
- Acceptable pretreatment clinical laboratory results.
- Life expectancy of greater than 12 weeks.
You may not qualify if…
- Have received previous treatment with INNO-105.
- Have an active, uncontrolled systemic infection considered opportunistic, life threatening, or clinically significant at the time of treatment.
- Are pregnant or lactating.
- Have a psychiatric disorder(s) that would interfere with consent, study participation, or follow-up.
- Have received any chemotherapy, immunotherapy, vaccines, monoclonal antibodies, major surgery, or irradiation, whether conventional or investigational, within 2 weeks of treatment in this study.
- Have not recovered from acute toxicity of all previous therapy prior to enrollment.
- Have symptomatic or untreated central nervous system (CNS) metastases.
- Have a susceptibility to hypotension, bradycardia, and/or hypopnea, such as patients with known coronary heart disease, arrhythmias, cerebral vascular disease, and chronic obstructive airways disease (CO2-retaining).
Where it is running
- University of Maryland Greenebaum Cancer Center — Baltimore, Maryland, United States
- Mary Crowley Medical Research Center — Dallas, Texas, United States
Full record on ClinicalTrials.gov
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