Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer
Stopped early · Phase 3
Conditions studied: Carcinoma, Non-Small-Cell Lung
In brief
To assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or metastatic Non-Small-Cell Lung Cancer (NSCLC) and to compare it to the efficacy and safety of paclitaxel
Key facts
- Study ID
- NCT00254891
- Run by
- Pfizer
- People needed
- 828
- Starts
- 2005-11-01
- Expected to finish
- 2008-07-01
- Last updated by the study team
- 2015-03-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Advanced Non-Small-Cell Lung Cancer (NSCLC) stage IIIB with pleural effusion or stage IV
- No prior systemic treatment for Non-Small-Cell Lung Cancer (NSCLC)with chemotherapy, immunotherapy, biologic response modifiers or other investigational drugs
- Eastern Cooperative Oncology Performance Status (ECOG PS) 0 or 1
You may not qualify if…
- Small cell or carcinoid lung cancer
- Known Central Nervous System (CNS) metastasis
- Pre-existing auto-immune or antibody mediated diseases
Where it is running
- Pfizer Investigational Site — Hot Springs, Arkansas, United States
- Pfizer Investigational Site — Chula Vista, California, United States
- Pfizer Investigational Site — La Mesa, California, United States
- Pfizer Investigational Site — Oceanside, California, United States
- Pfizer Investigational Site — Palm Springs, California, United States
- Pfizer Investigational Site — San Diego, California, United States
- Pfizer Investigational Site — San Francisco, California, United States
- Pfizer Investigational Site — Atlanta, Georgia, United States
- Pfizer Investigational Site — Atlanta, Georgia, United States
- Pfizer Investigational Site — Atlanta, Georgia, United States
- Pfizer Investigational Site — Atlanta, Georgia, United States
- Pfizer Investigational Site — Atlanta, Georgia, United States
- Pfizer Investigational Site — Decatur, Georgia, United States
- Pfizer Investigational Site — Fayetteville, Georgia, United States
- Pfizer Investigational Site — Macon, Georgia, United States
- Pfizer Investigational Site — Marietta, Georgia, United States
- Pfizer Investigational Site — Tucker, Georgia, United States
- Pfizer Investigational Site — Rockford, Illinois, United States
- Pfizer Investigational Site — Jefferson, Indiana, United States
- Pfizer Investigational Site — New Albany, Indiana, United States
- Pfizer Investigational Site — Cedar Rapids, Iowa, United States
- Pfizer Investigational Site — Dubuque, Iowa, United States
- Pfizer Investigational Site — Lexington, Kentucky, United States
- Pfizer Investigational Site — Louisville, Kentucky, United States
- Pfizer Investigational Site — Little Rock, Alaska, United States
Full record on ClinicalTrials.gov
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