BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.

Completed · Phase 1/Phase 2

Conditions studied: Acute Kidney Failure

In brief

Use of BNP (nesiritide) vs placebo to help protect kidney function in patients undergoing heart bypass surgery.

Key facts

Study ID

NCT00252200

Run by

Mayo Clinic

People needed

40

Starts

2003-03-01

Expected to finish

2007-10-01

Last updated by the study team

2009-09-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients > 18 years old, undergoing cardiac surgery requiring cardiopulmonary bypass with baseline creatinine clearance < 50 ml/min and who are not dialysis dependent.

You may not qualify if…

• Cardiogenic shock or hypotension with systolic BP < 90 mmHg.
• Patients with acute or chronic aortic dissection.
• Patients who are enrolled in other studies that have an effect the renal function.

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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