Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging

Completed

Conditions studied: Atherosclerosis

In brief

The purpose of this study is to learn what changes in blood vessel contraction may occur as a result of a disease of the vessel that requires surgery. The study will examine the calcium channels present in the vessels being operated on, and the genes that may alter blood vessel function. Possible variation in these genes may change the kind of calcium channels present in blood vessels.

Key facts

Study ID

NCT00251615

Run by

National Institute on Aging (NIA)

People needed

18

Starts

2012-08-01

Expected to finish

2012-08-01

Last updated by the study team

2012-08-06

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 21 and older
• Scheduled for vascular surgery

You may not qualify if…

• Unwillingness to be subjected to diagnostic and/or therapeutic procedures that are deemed not necessary for clinical management
• Volunteers deemed too fragile to participate in the study by the principal investigator (PI) or the attending physician
• Inability to obtain informed consent from either the volunteer or the responsible party (durable power of attorney [DPA]) for the volunteer, with the volunteer's assent

Where it is running

• National Institute on Aging, Harbor Hospital — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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