Cognitive Rehabilitation in Schizophrenia
Completed · Not applicable
Conditions studied: Cognitive Impairment, Schizophrenia
In brief
The study will investigate the viability of two cognitive rehabilitation strategies to improve functional outcomes for people with schizophrenia. Many people with schizophrenia experience impairments in cognitive function which limit their abilities. These impairments have been shown to precede the onset of illness and represent a vulnerability factor which is exacerbated by emerging psychotic symptoms. These impairments affect a range of functional domains including symptom severity, work function, symptom management, treatment, and overall quality of life. Recognizing the link between cognitive impairment and function, a few clinicals and researchers have attempted to remediate cognitive impairments by providing cognitive retraining programs similar to those used in traumatic brain injured patients or adaptive skills training. Cognitive retraining involves repetitive exercises to increase elemental cognitive functions including memory, attention, psychomotor speed, planning, and cognitive flexibility. Adaptive skill training involves didactic group exercises in social skills, activities of daily living, and symptom management. Each approach has demonstrated some rehabilitation benefits. This study will investigate the effectiveness of a combination of these two approaches on outcomes in schizophrenia.
Key facts
- Study ID
- NCT00248794
- Run by
- VA Office of Research and Development
- People needed
- 59
- Starts
- 2004-06-01
- Expected to finish
- 2009-10-01
- Last updated by the study team
- 2016-05-25
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Clinical diagnosis of schizophrenia or schizoaffective disorder. Between the ages of 18-65. Stable medication regime (no changes in last 30 days)Minimum of 30 days since last hospitalization. No hx of TBI
You may not qualify if…
- Current Substance abuse, no comorbid neurological disease
Where it is running
- VA Connecticut Health Care System (West Haven) — West Haven, Connecticut, United States
Full record on ClinicalTrials.gov
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