Mechanisms of Adaptation in Human Short Bowel Syndrome
Completed
Conditions studied: Short Bowel Syndrome
In brief
This is an observational, natural history trial of mechanisms of gut adaptation in adult short bowel syndrome (SBS). Patients with SBS (\< 200 cm small bowel ± colon) will be studied initially 2-9 months after the last small bowel resection and again exactly 6 months after the initial study. GCRC-studies will examine intestinal nutrient absorption, gut barrier functions and gut mucosal biopsy specimens for markers of nutrient transport and cell proliferation and apoptosis.
Key facts
- Study ID
- NCT00248573
- Run by
- Emory University
- People needed
- 32
- Starts
- 2004-10-01
- Expected to finish
- 2013-07-01
- Last updated by the study team
- 2013-12-17
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.
Where it is running
- Cleveland Clinic Foundation — Cleveland, Ohio, United States
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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