A Peri-intubation Oral Intervention to Reduce Oral Flora and VAP

Completed · Phase 4

Conditions studied: Pneumonia

In brief

The purpose of this study is determine if a single, early dose of chlorhexidine applied within 12 hours after endotracheal tube insertion will reduce the bacteria in the oral cavity and the incidence of pneumonia in trauma victims.

Key facts

Study ID

NCT00248300

Run by

Virginia Commonwealth University

People needed

156

Starts

2005-08-01

Expected to finish

2008-08-01

Last updated by the study team

2015-11-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• trauma victim
• endotracheal intubation within the past 12 hours
• mechanical ventilation

You may not qualify if…

• diagnosis of pneumonia at the time of intubation
• previous endotracheal tube placement in the last 48 hours
• burn injuries

Where it is running

• Virginia Commonwealth University School of Nursing — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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