RSV Disease in the Elderly
Completed
Conditions studied: Respiratory Infections, Acute, Respiratory Syncytial Virus
In brief
Respiratory syncytial virus (RSV) causes sickness and deaths in older people every winter. This study will investigate how aging affects the body's immune response (body's response to disease) to RSV. About 2000 people, age 21 and older, who reside in the upstate NY area, will be recruited. Two groups of subjects will be studied. The 1st group of volunteers will be recruited prior to the start of RSV season in year 1 of the study. These volunteers will include healthy people and people with various medical conditions. The 2nd group of volunteers will be patients admitted to Rochester General Hospital for acute respiratory illness. Procedures will include drawing blood from a vein in the arm (2 tablespoons), collecting nasal swabs, and collecting sputum. Volunteers may participate in study related procedures for up to 3 years.
Key facts
- Study ID
- NCT00246480
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 1401
- Starts
- 2005-10-03
- Expected to finish
- 2008-05-28
- Last updated by the study team
- 2019-02-04
Who can join
Age: 21 and older, up to 99. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Prospective Cohort
- Greater than or equal to 21 years of age
- Able to provide written consent
- Telephone contact available
- Will reside in the Upstate New York area throughout the winter months
- Hospital Cohort
- Greater than or equal to 21 years of age
- Able to provide written consent or legal guardian able to provide written consent
- Telephone contact available
- Symptoms of respiratory tract infection for less than or equal to 30 days duration. Symptoms can be all or any of the following: nasal congestion, cough, new or increased sputum or dyspnea, sore throat, with or without fever
You may not qualify if…
- Prospective Cohort
- Known immunosuppressive condition including: HIV, active cancer currently receiving chemotherapy, hematological malignancy, autoimmune disorders.
- Documented RSV infection in the previous year
- Participation in previous RSV vaccine study
- Hospital Cohort
- Known immunosuppressive condition including: HIV, active cancer currently receiving chemotherapy, hematological malignancy, autoimmune disorders.
- Symptoms of a respiratory infection for longer than 30 days.
- Participation in prior RSV vaccine study
Where it is running
- Rochester General Hospital — Rochester, New York, United States
Full record on ClinicalTrials.gov
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