Magnetic Resonance Imaging Study of Geriatric Depression

Completed · Not applicable

Conditions studied: Major Depressive Disorder

In brief

The purpose of this study was to use Magnetic Resonance Images to further our understanding of predictors and markers of treatment response and non-response in geriatric depression. We hypothesized that concentrations of high energy metabolites would be lower in depressed elderly compared to non-depressed.

Key facts

Study ID

NCT00245557

Run by

Mclean Hospital

People needed

43

Starts

2004-11-01

Expected to finish

2008-08-01

Last updated by the study team

2017-03-30

Who can join

Age: 55 and older, up to 89. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• DSM- IV (Diagnostic and Statistical Manual of Mental Disorders, 4th Edition) diagnostic criteria for major depressive disorder
• Hamilton Depression Scale- 17 item version score of 18 or higher
• Must speak English
• Women must be post-menopausal

You may not qualify if…

• A current or pervious psychiatric disorder other than MDD
• A current unstable medical condition
• A pacemaker or metal implant
• History of alcohol or drug dependence or abuse within the past year
• Current prescription of excluded medications
• Use of a drug within the last 30 days that was not approved for use by governmental authorities.
• If you or a family member works at McLean Hospital

Where it is running

• McLean Hospital — Belmont, Massachusetts, United States

Full record on ClinicalTrials.gov

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