Study of Tamsulosin and/or Dutasteride to Relieve Urinary Symptoms After Brachytherapy for Localized Prostate Cancer

Completed · Phase 3

Conditions studied: Prostate Cancer

In brief

The purpose of this study is to determine whether a drug named tamsulosin (Flomax), or another drug named dutasteride (Avodart), or a combination of these two drugs is effective in improving urinary symptoms and decreasing the rate of intermittent self-catheterization after prostate brachytherapy.

Key facts

Study ID

NCT00244309

Run by

Case Comprehensive Cancer Center

People needed

348

Starts

2005-11-01

Expected to finish

2006-06-01

Last updated by the study team

2011-05-04

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Patient is eligible for a prostate implant
• Patient is greater than 18 years of age
• Patient is able to give informed consent
• Patient does not currently take Flomax, Dutasteride or Finasteride
• Patient does not have a known hypersensitivity reaction to Flomax or Dutasteride

You may not qualify if…

• Patients who have a known hypersensitivity reaction to tamsulosin, dutasteride or finasteride and those patients who are already on any prior to prostate implantation
• Patients who are taking a PDE-5 inhibitor including sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) are ineligible to participate unless they are willing to discontinue using those drugs one week prior to their implant and for three months after the implant

Where it is running

• Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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