MIRAGE: Multi-Institutional Research in Alzheimer's Genetic Epidemiology

Completed

Conditions studied: Alzheimer's Disease

In brief

The goal of MIRAGE is to evaluate the association of genetic and non-genetic risk factors for Alzheimer's Disease.

Key facts

Study ID

NCT00239759

Run by

National Institute on Aging (NIA)

People needed

2000

Starts

2002-09-01

Expected to finish

2008-06-01

Last updated by the study team

2009-02-25

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• NOTE: This trial accepts patients with Probable AD, and their cognitively normal brothers or sisters
• Probable or definite AD by NINCDS-ADRDA criteria
• Living siblings who are cognitively normal as measured by a brief standardized cognitive assessment
• Ages 60 and over for Alzheimer's disease patients
• Ages 50 and over for cognitively normal siblings

You may not qualify if…

• Early onset Alzheimer's disease attributed to APP, PS1 or PS2 gene mutations
• History of clinical stroke
• Siblings whose cognitive assessment does not meet study criteria
• Pacemaker or other contraindication to MRI

Where it is running

• University of Alabama — Birmingham, Alabama, United States
• Sun Health Research Institute — Sun City, Arizona, United States
• Rancho Los Amigos National Rehabilitation Center/University of Southern California — Downey, California, United States
• University of California, Davis — Sacramento, California, United States
• Howard University — Washington D.C., District of Columbia, United States
• University of Miami School of Medicine — Miami Beach, Florida, United States
• Morehouse School of Medicine — Atlanta, Georgia, United States
• Pacific Health Research Institute — Honolulu, Hawaii, United States
• Indiana University School of Medicine — Indianapolis, Indiana, United States
• Boston University School of Medicine — Boston, Massachusetts, United States
• Cornell Medical University — New York, New York, United States
• Case Western Reserve University — Cleveland, Ohio, United States
• University of British Columbia — Vancouver, British Columbia, Canada
• Technical University of Munich — Munich, Germany
• G. Papanicolaou Hospital — Exholi Thessaloniki, Greece

Full record on ClinicalTrials.gov

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