Vitamin D Deficiency: Bone Loss and Vascular Dysfunction

Completed · Not applicable

Conditions studied: Postmenopausal Women

In brief

To learn if there is a connection between low vitamin D level and hardening of the arteries.

Key facts

Study ID

NCT00235586

Run by

University of Kansas

People needed

40

Starts

2004-04-01

Expected to finish

2007-09-01

Last updated by the study team

2007-09-20

Who can join

Age: 50 and older, up to 90. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Females ages 50-70 with ability to give informed consent
• One year past last menstrual period
• 20 women with Vitamin D levels < 15 mg/ml
• 20 women with Vitamin D levels > 30 mg/ml

You may not qualify if…

• women receiving hormone replacement therapy
• women receiving medication known to effect vascular compliance, including anti-hypertension medications
• subjects receiving therapy for osteoporosis
• hyperthyroidism
• untreated hypothyroidism
• history of metabolic bone disease
• current or previous use of medications known to accelerate bone loss
• chronic liver disease
• chronic renal disease
• diabetes mellitus
• obesity, BMI > 24

Where it is running

• University of Kansas Medical Center — Kansas City, Kansas, United States

Full record on ClinicalTrials.gov

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