The Effect of Aerobic Exercise on Learning After Stroke

Completed · Phase 1

Conditions studied: Stroke

In brief

Determine if attaining aerobic fitness is beneficial in producing cortical neuroplasticity in individuals with chronic stroke.

Key facts

Study ID

NCT00228306

Run by

University of Kansas

People needed

38

Starts

2005-09-01

Expected to finish

2009-12-01

Last updated by the study team

2012-05-01

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Single ischemic stroke occuring 6-72 months prior
• Fugl-Meyer score (upper + lower extremity) 45 or greater
• Mini mental status score of >23
• approval of the subject's medical doctor

You may not qualify if…

• already performing >20 min of cardiovascular exercise 3x/wk or more
• alcohol consumption of >2 oz. liquor, 8 oz. wine or 24 oz beer/day
• cardiac history of unstable angina, recent myocardia infarction within the last 3 months, congestive heart failure, significant valve dysfunction
• medical history of recent hospitalization (> 3 months) for medical illness
• symptomatic peripheral arterial occlusive disease
• orthopedic or chronic pain conditions restricting exercise
• pulmonary or renal failure
• active cancer
• unstable hypertension (>160/100 mmHg)
• diabetes mellitus (fasting glucose > 180 NG./dk, HgA1C > 10%) that is unable to be controlled < month
• receptive or expressive aphasia as indicated on MMSE
• multiple strokes or other neuromuscular conditions
• major depression that is untreated using the Beck depression inventory

Where it is running

• University of Kansas Medical Center — Kansas City, Kansas, United States

Full record on ClinicalTrials.gov

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