Natural Supplements for Unipolar Depression

Completed · Phase 4

Conditions studied: Unipolar Depression

In brief

This study is being conducted to determine the clinical response rate for the regimen of L-methionine, betaine and folate for unipolar depression.

Key facts

Study ID

NCT00226356

Run by

Cambridge Health Alliance

People needed

20

Starts

2004-12-01

Expected to finish

2008-09-17

Last updated by the study team

2017-04-18

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• DSM-IV diagnosis of a MDD or DDNOS; clinical indication for treatment of current depressive symptoms; HDS > 18; women of reproductive potential must use an acceptable method of birth control

You may not qualify if…

• Treatment with another psychotropic drug; history of mania or hypomania; history of bipolar illness in first-degree relatives; active homicidality; pregnant; trying to become pregnant, or nursing; unstable medical condition; current substance abuse in the past month; history of sulfa allergy

Where it is running

• Cambridge Health Alliance — Cambridge, Massachusetts, United States

Full record on ClinicalTrials.gov

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