Early Tobacco Abstinence - 5
Stopped early · Phase 1
Conditions studied: Tobacco Use
In brief
This proposal will conduct a prospective examination of the clinical course (intensity, content and duration) of tobacco (nicotine) abstinence effects in male and female smokers who are either heavy/light alcohol drinkers with/without depressive symptoms.
Key facts
- Study ID
- NCT00224965
- Run by
- National Institute on Drug Abuse (NIDA)
- People needed
- 140
- Expected to finish
- 2004-10-01
- Last updated by the study team
- 2017-01-12
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- between ages 18-60 years; (2) able to read and write English (3) SMOKER: Smoking >10 cigarettes per day for at least 1 year, with CO > 10 ppm, and blood cotinine concentration of 150 ng/ml or greater, FTND scores > 5.
- (4) DEPRESSED SUBJECT: Not meeting SCID criteria for current major depression or more than one past major depressive episode, but having scores > 10 on the CES-D indicating presence of depressive symptomatology (5) NON-DEPRESSED SUBJECT: Not meeting SCID criteria for current major depression or more than one past major depressive episode, CES-D scores <10.
- (6) HEAVY DRINKER: Not meeting SCID criteria for current alcohol dependence; drinking 20 or more drinks per month.
- (7) LIGHT DRINKER: Not meeting SCID criteria for current alcohol dependence; drinking ten drinks or less per month
You may not qualify if…
- Current dependence on cocaine, marijuana, opiates or alcohol
- Positive urine screen for marijuana, cocaine or opiates at any appointment after the intake appointment.
- Regular use of any psychoactive drugs including anxiolytics and antidepressants;
- Current major depression or other psychiatric conditions
- Subjects with any significant, untreated current medical conditions condition such as neurological, endocrine, cardiovascular, renal, liver, thyroid pathology or on medications for any recent medical events 6) Pregnant or lactating women -
Where it is running
- Yale University, Dept. of Psychiatry — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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