Electrical Stimulation After Total Knee Arthroplasty

Status unconfirmed · Phase 1

Conditions studied: Total Knee Arthroplasty, Osteoarthritis

In brief

Total knee arthroplasty (TKA) is performed more than 300,000 times a year in the United States, most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Voluntary exercise has been ineffective at restoring quadriceps strength after TKA. The aims of this study are: 1) to assess the effectiveness of high-level neuromuscular electrical stimulation as an adjunct to ongoing intensive, early rehabilitation in restoring quadriceps strength and improving the functional outcome after primary TKA, and 2) to identify the physiological and morphological bases for improvements in quadriceps strength and functional outcome.

Key facts

Study ID

NCT00224913

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

200

Starts

2002-03-01

Last updated by the study team

2005-10-12

Who can join

Age: 45 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• TKA for unilateral tricompartmental knee OA

You may not qualify if…

• Insulin dependent diabetes
• neurological conditions
• other lower extremity orthopedic problems that affect function
• BMI>40

Where it is running

• University of Delaware — Newark, Delaware, United States (enrolling)

Full record on ClinicalTrials.gov

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