Effect of Age on Latanoprost 0.005% in Patients With Glaucoma

Completed · Phase 4

Conditions studied: Glaucoma

In brief

Latanoprost is a commonly used treatment for glaucoma. Because of its mechanism of action, it is plausible that the age of a patient using the medication may affect its efficacy and time of onset. We are going to study the effectiveness of Latanoprost in people of different ages, to see if it changes based on the age of the patient.

Key facts

Study ID

NCT00224289

Run by

Yale University

People needed

17

Starts

2005-03-01

Expected to finish

2009-04-01

Last updated by the study team

2012-12-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• diagnosis of open angle glaucoma,
• pseudoexfoliation glaucoma, pigmentary glaucoma or ocular hypertension in one or both eyes;
• IOP above their target pressure as determined by a glaucoma specialist;
• willingness to participate in the study.

You may not qualify if…

• hypersensitivity to any of the components of the treatment medication;
• previous use of topical prostaglandins;
• documented ocular infection or intraocular inflammation within the past year;
• previous filtering surgery or complicated cataract surgery;
• active corneal disease;
• presence of cystoid macular edema;
• laser trabeculoplasty or any other ocular laser procedure within the past three months.

Where it is running

• Yale Eye Center — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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