Cytokine Regulation of Periradicular Pain in Humans

Completed

Conditions studied: Chronic Apical Periodontitis of Pulpal Origin

In brief

This clinical trial evaluates the role of cytokines in patients needing root canal treatment with diagnosis of necrotic pulp and chronic apical periodontitis

Key facts

Study ID

NCT00223470

Run by

The University of Texas Health Science Center at San Antonio

People needed

9

Starts

2002-10-01

Expected to finish

2008-06-01

Last updated by the study team

2012-03-09

Who can join

Age: 16 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient must be at least 16 years of age.
• Clinical indication for Non-Surgical Root Canal Therapy (NSRCT).
• 1st or 2nd maxillary or mandibular molar
• Diagnosis must be Chronic Apical Periodontitis (CAP) with or without symptoms.
• Intact, mature apices.
• ASA I or II

You may not qualify if…

• Failure to meet any of the above
• Previous NSRCT
• Previous pulpotomy or pulpectomy
• Suppurative apical periodontitis
• Patients taking medications which can affect their pain rating or medications which effect their immune system ( such as glucocorticoids)

Where it is running

• Univerity of Texas Health Science Center at San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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