Trial of Ropinirole in Motor Recovery After Stroke

Completed · Phase 2 · Has a placebo group

Conditions studied: Cerebrovascular Accident, Hemiparesis

In brief

The purpose of this study is to assess efficacy, as well as safety, of Ropinirole in improving movement among patients with chronic stroke.

Key facts

Study ID: NCT00221390
Run by: University of California, Irvine
People needed: 52
Starts: 2003-10-01
Expected to finish: 2007-05-01
Last updated by the study team: 2016-11-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Stroke onset 4 weeks-12 months prior
Stroke is radiologically confirmed as either (a) ischemic or (b) hemorrhagic
Minimum age 18
No significant pre-stroke disability
No other stroke in previous 3 months
Absence of major depression
Fugl-Meyer (FM) motor score of 23-83 out of 100
Functional Independence Measure (FIM) ambulation-subscore of 3 or more, and 50 foot walk takes longer than 15 seconds

You may not qualify if…

Significant daytime somnolence or any substantial decrease in alertness, language reception, or attention
Pregnant or lactating
Advanced liver, kidney, cardiac, or pulmonary disease
Orthostatic hypotension
Current use of ciprofloxacin, a centrally acting dopamine agonist, or a centrally active dopamine antagonist
A terminal medical diagnosis consistent with survival < 1 year
Coexistent major neurological disease
Coexistent major psychiatric disease
A history of significant alcohol or drug abuse in the prior 3 years
A coexistent disease characterized by an abnormality of CNS dopaminergic tone
Current enrollment in another investigational study related to stroke or stroke recovery
Contraindication to ropinirole prescription

Where it is running

University of California, Irvine Medical Center — Orange, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.