Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children

Completed · Phase 2/Phase 3

Conditions studied: Tourette Syndrome, Tic Disorders

In brief

This study will determine the effectiveness of cognitive behavior therapy (CBT) with habit reversal training (HRT) in treating chronic tic disorders (CTDs) in children and adolescents.

Key facts

Study ID

NCT00218777

Run by

Tourette Association of America

People needed

120

Starts

2004-12-01

Expected to finish

2007-05-01

Last updated by the study team

2015-12-14

Who can join

Age: 9 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets DSM-IV diagnostic criteria for chronic tic disorder (chronic motor or vocal tic disorder or Tourette syndrome)
• Score of at least 3 on the Clinical Global Impressions Severity Scale
• Score of at least 14 on the Yale Global Tic Severity Scale (YGTSS) or at least 10 for individuals with motor tics only
• Unmedicated or currently on a stable medication treatment for tics, obsessive compulsive disorder (OCD), ADHD, anxiety, and/or depressive disorder for at least 6 weeks, with no planned changes for the duration of study participation
• Child speaks English

You may not qualify if…

• Score greater than 30 on the YGTSS
• IQ less than 80 on the Wechsler Abbreviated Scale of Intelligence (WASI)
• Meets DSM-IV criteria for substance abuse or dependence within the 3 months prior to study entry
• Meets DSM-IV criteria for conduct disorder within the 3 months prior to study entry
• Lifetime DSM-IV diagnosis of pervasive developmental disorder, mania, or psychotic disorder
• Any serious psychiatric, psychosocial, or neurological condition (i.e., OCD, ADHD, major depressive disorder, anxiety, severe aggression, or family discord) requiring immediate treatment other than what is provided in the current study (i.e., medication, school intervention, or family therapy)
• Previous treatment with four or more sessions of HRT for tics

Where it is running

• UCLA Child OCD, Anxiety, and Tic Disorders Program — Los Angeles, California, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• University of Wisconsin-Milwaukee — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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