Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

Completed

Conditions studied: Heroin Dependence, Opioid-Related Disorders

In brief

The purpose of this study is to determine whether knowledge of post-session hydromorphone (HYD) availability reduces drug seeking behavior in heroin dependent individuals.

Key facts

Study ID

NCT00218361

Run by

Wayne State University

People needed

16

Starts

2005-08-01

Last updated by the study team

2012-06-05

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Opioid dependent, as determined by the structured clinical interview for DSM-IV (SCID) and Addiction Severity Index (ASI)
• Positive urine test for opiates
• Willing to use an adequate form of contraception for the duration of the study
• Reads and writes English

You may not qualify if…

• Psychiatric illness, as determined by the DSM-IV criteria
• History of or current neurological disease, including structural abnormalities, seizures, infection, peripheral neuropathy, and head traumas
• History of cardiovascular disease, myocardial infarction, chest pain, or edema
• Systolic blood pressure greater than 160 mm Hg or less than 95 mm Hg; PR diastolic blood pressure greater than 95 mm Hg
• Pulmonary disease, including obstructive pulmonary disease, cor pulmonale, tuberculosis, and asthma
• Systemic disease (e.g., endocrinopathies, liver or kidney failure, myxedema, hypothyroidism, Addison's disease, autoimmune disease)
• Current alcohol or sedative drug dependence
• Pregnant or breastfeeding
• Currently receiving treatment for opioid dependence
• Known phobia of injections

Where it is running

• Wayne State University — Detroit, Michigan, United States

Full record on ClinicalTrials.gov

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