Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

Completed

Conditions studied: Heroin Dependence, Opioid-Related Disorders

In brief

The purpose of this study is to determine whether the opportunity to take free supplemental hydromorphone (HYD) influences drug seeking behavior in heroin dependent individuals.

Key facts

Study ID

NCT00218309

Run by

National Institute on Drug Abuse (NIDA)

People needed

16

Starts

2003-09-01

Expected to finish

2005-07-01

Last updated by the study team

2017-01-12

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current opiate dependence, verified by the structured clinical interview for DSM-IV (SCID) and Addiction Severity Index (ASI)
• Positive urine test for opiates
• Agreement to use adequate contraception for the duration of the study
• Able to read and write English

You may not qualify if…

• DSM-IV diagnosis of a psychiatric illness
• History of or current neurological disease, including structural brain abnormalities, seizures, infection, peripheral neuropathy, and head trauma
• History of cardiovascular disease, myocardial infarction, chest pain, edema, systolic blood pressure greater than 160 mm Hg or less than 95 mm Hg, or diastolic blood pressure greater than 95 mm Hg
• Pulmonary disease, including obstructive pulmonary disease, cor pulmonale, tuberculosis, and asthma
• Systemic diseases, such as endocrinopathies, liver or kidney failure, myxedema, hypothyroidism, Addison's disease, or autoimmune disease
• Current alcohol or sedative drug dependence
• Pregnant or breastfeeding
• Currently receiving treatment for opioid dependence
• Known phobia of injections

Where it is running

• Wayne State University — Detroit, Michigan, United States

Full record on ClinicalTrials.gov

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