Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence

Completed · Phase 2

Conditions studied: Cocaine Abuse, Cocaine-Related Disorders

In brief

Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to examine the effectiveness of levodopa and carbidopa in treating cocaine dependent individuals. In addition, this study will examine the effects of incentive rewards for treatment compliance.

Key facts

Study ID

NCT00218075

Run by

The University of Texas Health Science Center, Houston

People needed

200

Starts

2000-03-01

Expected to finish

2007-10-01

Last updated by the study team

2016-01-05

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets DSM-IV criteria for current cocaine dependence
• Provides at least one positive urine test for cocaine during study screening
• Good general health, based on a physical exam, lab tests, and an electrocardiogram
• Reads and writes English at a sixth grade level

You may not qualify if…

• Current Axis I depressive, psychotic, or anxiety disorder
• Currently in jail
• Pregnant or breastfeeding
• Requires certain medications

Where it is running

• University of Texas Health Science Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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