Effect of Yohimbine on Colon Transit
Completed · Phase 1/Phase 2
Conditions studied: Healthy Volunteers
In brief
This study is being done to learn if yohimbine, a naturally occurring drug, affects the speed at which food travels through the stomach, intestines and colon, and if yohimbine affects the amount of liquid you can drink in a short period of time. Understanding how yohimbine works on the gut may help develop new treatments for patients with constipation. Yohimbine has been approved by the Food and Drug Administration (FDA) for routine clinical use, however, its use as proposed in this study is considered investigational.
Key facts
- Study ID
- NCT00217048
- Run by
- Mayo Clinic
- People needed
- 30
- Starts
- 2005-06-01
- Expected to finish
- 2005-10-01
- Last updated by the study team
- 2009-04-29
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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