ATM Variants in Radiotherapy Patients

Completed

Conditions studied: Radiotherapy

In brief

The purpose of this study is to compare the baseline incidence of variant alleles in the ATM and/or other DNA repair genes present in the Native American population versus the non-Native American population. It is thought that a higher baseline incidence of the variant alleles in the ATM gene may correlate to higher rates and higher grades of radiation toxicities noted in the Native American population.

Key facts

Study ID

NCT00214227

Run by

University of Wisconsin, Madison

People needed

60

Starts

2007-12-01

Expected to finish

2013-01-01

Last updated by the study team

2019-11-19

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Indication for radiotherapy.
• Ability or desire to donate a blood sample and be followed closely for radiation toxicities

Where it is running

• University of Wisconsin Hospital and Clinics — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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