The Effect of Salmeterol on Eosinophil (EOS) Function

Completed · Not applicable · Has a placebo group

Conditions studied: Allergic Asthma

In brief

This study is designed to test the hypothesis that salmeterol use, and not fluticasone use or the combination treatment with fluticasone and salmeterol, is associated with a greater number of sputum eosinophils following antigen challenge and, under these circumstances, the migrating peripheral blood eosinophils are less adherent.

Key facts

Study ID

NCT00214019

Run by

University of Wisconsin, Madison

People needed

36

Starts

2003-11-01

Expected to finish

2008-01-01

Last updated by the study team

2017-11-21

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18-55 years of age
• history of asthma symptoms for the previous 6 months
• Forced Expiratory Value (FEV1) >75% of predicted
• positive prick skin test to cat, house dust mite or ragweed

You may not qualify if…

• history of life threatening asthma or anaphylaxis
• current smoker
• pregnant or breast-feeding
• evidence of an upper respiratory infection within 4 weeks of screening

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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